Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975760 | 0.93 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL92396 | 0.88 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL28415835 | 0.85 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3MAPT | |
| Phosphine SCHEMBL28991719 | 0.85 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3MAPT | |
| Methane SCHEMBL28815257 | 0.85 | ESR1 (0.46) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL126319 | 0.85 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL103830 | 0.85 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL15975758 | 0.85 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL12879524 | 0.85 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL15975757 | 0.85 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926383-B2 | Biocompatible three dimensional matrix for the immobilization of biological substances | LEUKOCARE AG (DE) | 2018-03-27 | — | — | US | disclosed |
| EP-2021374-B1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2011-09-21 | — | — | EP | disclosed |
| US-20100291665-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20090269778-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2009-10-29 | — | — | US | disclosed |
| WO-2009059784-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058335-A1 | Biocompatible three dimensional matrix for the immobilization of biological substances | Leukocare AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| EP-2021374-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | Leukocare AG (DE) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007128550-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2007-11-15 | — | — | WO | disclosed |
| EP-1852443-A1 | Biocompatible three dimensional matrix for the immobilization of biological substances | Leukocare AG (DE) | 2007-11-07 | — | — | EP | disclosed |