Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 3/20 | 0.56 |
| ▸ | PAK1 | Q13153 | 8/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20408818 | 0.88 | CYP2C9 (0.49) | MAP2K4PAK1CYP2C9CYP3A4 | |
| SCHEMBL20408810 | 0.88 | MAP2K4 (0.73) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL24523141 | 0.84 | MAP2K4 (0.55) | MAP2K4PAK1CYP2C9CYP2D6 | |
| SCHEMBL20408845 | 0.83 | MAP2K4 (0.75) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL27101478 | 0.83 | MAP2K4 (0.59) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL29725808 | 0.83 | MAP2K4 (0.75) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL29898532 | 0.83 | MAP2K4 (0.59) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL20408718 | 0.83 | MAP2K4 (0.53) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL20408838 | 0.83 | BRAF (0.53) | PAK1CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL20408816 | 0.75 | CYP2C9 (0.57) | MAP2K4PAK1CYP2C9CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3571200-B1 | PROTEIN KINASE INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH | HEPAREGENIX GMBH (DE) | 2022-06-22 | — | — | EP | disclosed |