Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528000 | 0.90 | KDM4E (0.44) | DYRK1AKCNH2GSK3BNPY5RMEN1 | |
| SCHEMBL24527994 | 0.89 | KDM4E (0.45) | DYRK1AKCNH2GSK3BNPY5RMEN1 | |
| SCHEMBL24528219 | 0.86 | DYRK1A (0.40) | DYRK1AMKNK1PIK3CAMAPK10KCNH2 | |
| SCHEMBL24528193 | 0.86 | DYRK1A (0.40) | DYRK1AMKNK1PIK3CAMAPK10KCNH2 | |
| SCHEMBL17704962 | 0.86 | KDM4E (0.40) | DYRK1AMKNK1NR3C1KCNH2GSK3B | |
| SCHEMBL15945736 | 0.85 | CDK4 (0.42) | DYRK1AMKNK1NR3C1PIK3CAMAPK10 | |
| SCHEMBL11965527 | 0.85 | CDK4 (0.42) | DYRK1AMKNK1NR3C1PIK3CAMAPK10 | |
| SCHEMBL25946458 | 0.85 | KDM4E (0.44) | DYRK1AMKNK1PIK3CAMAPK10KCNH2 | |
| SCHEMBL17704977 | 0.85 | KDM4E (0.44) | DYRK1AKCNH2GSK3BNPY5RKDM4E | |
| SCHEMBL17265101 | 0.85 | KDM4E (0.44) | DYRK1AKCNH2GSK3BNPY5RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129113-A1 | NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |