SCHEMBL24528291 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK1	P28482	1/20	0.35

▸	AHR	P35869	3/20	0.34

▸	PDK2	Q15119	2/20	0.33

▸	PGR	P06401	2/20	0.33

▸	HRH4	Q9H3N8	2/20	0.33

▸	HRH2	P25021	1/20	0.33

▸	HRH1	P35367	1/20	0.33

▸	HRH3	Q9Y5N1	1/20	0.33

▸	P2RX4	Q99571	1/20	0.33

▸	DRD2	P14416	2/20	0.32

▸	DRD4	P21917	2/20	0.32

▸	PIM1	P11309	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24528517	0.92	PDK2 (0.36)	MAPK1PDK2PGRP2RX4PIM1
SCHEMBL24527786	0.86	P2RX4 (0.34)	MAPK1AHRP2RX4
SCHEMBL25625961	0.80	P2RX4 (0.44)	AHRP2RX4PIM1
SCHEMBL20202051	0.80	P2RX4 (0.38)	AHRP2RX4
SCHEMBL24569766	0.79	MAPT (0.35)	P2RX4
SCHEMBL17084429	0.79	PDK2 (0.38)	AHRPDK2
SCHEMBL24528289	0.78	PDK2 (0.40)	MAPK1PDK2HRH4HRH2HRH1
SCHEMBL24528520	0.78	—	—
SCHEMBL17084415	0.78	PDK2 (0.39)	PDK2
SCHEMBL24528547	0.77	PDK2 (0.30)	PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022131668-A1	NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME	주식회사 센텀머티리얼즈	2022-06-23	—	—	WO	disclosed