Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.86 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179813 | 0.93 | HCRTR2 (0.74) | HCRTR2SYKEPHB4RAF1BRAF | |
| SCHEMBL27179816 | 0.93 | HCRTR2 (0.74) | HCRTR2SYKEPHB4RAF1BRAF | |
| SCHEMBL29723555 | 0.93 | HCRTR2 (1.00) | HCRTR2SYKEPHB4 | |
| SCHEMBL24529569 | 0.93 | HCRTR2 (1.00) | HCRTR2SYKEPHB4 | |
| SCHEMBL27180395 | 0.93 | HCRTR2 (1.00) | HCRTR2SYKEPHB4 | |
| SCHEMBL27179811 | 0.93 | HCRTR2 (0.74) | HCRTR2SYKEPHB4RAF1BRAF | |
| SCHEMBL27180393 | 0.93 | HCRTR2 (1.00) | HCRTR2SYKEPHB4 | |
| SCHEMBL24529493 | 0.90 | HCRTR2 (0.82) | HCRTR2NTRK1EPHB4 | |
| SCHEMBL29723605 | 0.90 | HCRTR2 (0.82) | HCRTR2NTRK1EPHB4 | |
| SCHEMBL27179518 | 0.90 | HCRTR2 (0.82) | HCRTR2NTRK1EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |