Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.77 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529488 | 0.94 | HCRTR2 (0.75) | HCRTR2 | |
| SCHEMBL27180101 | 0.94 | HCRTR2 (0.75) | HCRTR2 | |
| SCHEMBL27181338 | 0.92 | HCRTR2 (0.73) | HCRTR2TTK | |
| SCHEMBL27181340 | 0.92 | HCRTR2 (0.73) | HCRTR2TTK | |
| SCHEMBL27181336 | 0.92 | HCRTR2 (0.73) | HCRTR2TTK | |
| SCHEMBL24529366 | 0.87 | HCRTR2 (0.86) | HCRTR2 | |
| SCHEMBL24529569 | 0.87 | HCRTR2 (1.00) | HCRTR2 | |
| SCHEMBL29723555 | 0.87 | HCRTR2 (1.00) | HCRTR2 | |
| SCHEMBL27180395 | 0.87 | HCRTR2 (1.00) | HCRTR2 | |
| SCHEMBL27180393 | 0.87 | HCRTR2 (1.00) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |