Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.63 |
| ▸ | CTSA | P10619 | 3/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180818 | 1.00 | HCRTR2 (0.63) | HCRTR2CTSAPOLQPSEN1PSEN2 | |
| SCHEMBL27180820 | 1.00 | HCRTR2 (0.63) | HCRTR2CTSAPOLQPSEN1PSEN2 | |
| SCHEMBL27181350 | 0.90 | HCRTR2 (0.66) | HCRTR2 | |
| SCHEMBL24529299 | 0.90 | HCRTR2 (0.66) | HCRTR2 | |
| SCHEMBL24529442 | 0.90 | HCRTR2 (0.62) | HCRTR2 | |
| SCHEMBL27181217 | 0.90 | HCRTR2 (0.62) | HCRTR2 | |
| SCHEMBL27181215 | 0.90 | HCRTR2 (0.62) | HCRTR2 | |
| SCHEMBL24529269 | 0.90 | HCRTR2 (0.65) | HCRTR2 | |
| SCHEMBL29723498 | 0.90 | HCRTR2 (0.65) | HCRTR2 | |
| SCHEMBL27180875 | 0.90 | HCRTR2 (0.65) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |