Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | FASN | P49327 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785794 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL7806557 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL6556128 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL1614406 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL2059489 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL3793137 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL23067684 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL17540751 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL21411170 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 | |
| SCHEMBL1614408 | 1.00 | PTPN1 (0.67) | PTPN1FASNKDM4ECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698609-A1 | Alpha-phosphorus substituted sulfinate derivatives as squalene synthetase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-28 | — | — | EP | claimed |
| EP-0595635-A1 | Alpha-phosphorous substituted sulfonate derivatives as squalene synthetase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1994-05-04 | — | — | EP | claimed |
| US-12292665-B2 | Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof | GAUZY LTD. (IL) | 2025-05-06 | — | — | US | disclosed |
| WO-2023213310-A9 | CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF | 太阳雨林(北京)生物医药有限公司 | 2025-02-20 | — | — | WO | disclosed |
| WO-2023213310-A1 | CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF | 太阳雨林(北京)生物医药有限公司 | 2023-11-09 | — | — | WO | disclosed |
| CN-115607677-A | Compound for preventing, preventing or treating microbial infection and preparation and application thereof | 太阳雨林(北京)生物医药有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114848656-A | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114788872-A | Compound for preventing, preventing or treating microbial infection and preparation and application thereof | 太阳雨林(北京)生物医药有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114569726-A | Compound for preventing, preventing or treating microbial infection and preparation method and application thereof | 太阳雨林(北京)生物医药有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-108289902-B | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-05-20 | — | — | CN | disclosed |
| US-20220050316-A1 | BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF | GAUZY LTD. (IL) | 2022-02-17 | — | — | US | disclosed |
| US-5567841-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| US-5543542-A | REACTING PHOSPHONOSULFONATE WITH OXIDIZING AGENT, REACTING PRODUCT WITH HYDROXYLAMINE PROTECTING AGENT, THEN WITH SILYL BROMIDE OR IODIDE | LAWRENCE R MICHAEL (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0710665-A1 | Phosphonosulfonate squalene synthetase inhibitor salts and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0698609-A1 | Alpha-phosphorus substituted sulfinate derivatives as squalene synthetase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5470845-A | Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| US-5447922-A | Anticholesterol agents and enzyme inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-09-05 | — | — | US | disclosed |
| EP-0656927-A1 | METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX | Sniaricerche S.C.P.A. (IT) | 1995-06-14 | — | — | EP | disclosed |
| WO-1995001410-A1 | METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX | SNIARICERCHE S.C.P.A. (IT) | 1995-01-12 | — | — | WO | disclosed |
| EP-0595635-A1 | Alpha-phosphorous substituted sulfonate derivatives as squalene synthetase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1994-05-04 | — | — | EP | disclosed |