Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 11/20 | 0.45 |
| ▸ | CA2 | P00918 | 11/20 | 0.45 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.45 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651672 | 0.91 | CA12 (0.46) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL19027343 | 0.81 | TLR8 (0.48) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL24533118 | 0.81 | STK17B (0.51) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL28420219 | 0.81 | KDM4E (0.43) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL14420521 | 0.81 | TDP1 (0.47) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL29651697 | 0.80 | STK17B (0.44) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL19741733 | 0.80 | STK17B (0.44) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL5531682 | 0.79 | TDP1 (0.48) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL14416000 | 0.79 | STK17B (0.43) | DYRK1ACA1CA2CA12CA9 | |
| SCHEMBL7056763 | 0.78 | STK17B (0.45) | DYRK1ACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133303-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |