Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.61 |
| ▸ | ACE | P12821 | 5/20 | 0.57 |
| ▸ | CPA1 | P15085 | 5/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.57 |
| ▸ | GNPAT | O15228 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534148 | 1.00 | MME (0.61) | MMEACECPA1ACE2GNPAT | |
| Benzene SCHEMBL27569477 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| Benzene SCHEMBL27550557 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL754129 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| Benzene SCHEMBL27550555 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL205548 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL627437 | 0.94 | MME (0.59) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL13968381 | 0.92 | MME (0.56) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL7772111 | 0.90 | MME (0.66) | MME | |
| SCHEMBL5492842 | 0.90 | MME (0.66) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133232-A1 | METHODS FOR MANUFACTURE OF SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint Pharmaceuticals, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |