Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699629 | 0.83 | PTPRB (0.50) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL8587434 | 0.83 | PTPRB (0.46) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL23303560 | 0.83 | PTPRB (0.46) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL19288099 | 0.83 | RAD52 (0.53) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL24534131 | 0.79 | PTPRB (0.41) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL24534174 | 0.79 | MEN1 (0.49) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL29827135 | 0.78 | PTPRB (0.53) | PTPRBKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL16029785 | 0.78 | PTPRB (0.65) | PTPRB | |
| SCHEMBL16029790 | 0.78 | PTPRB (0.65) | PTPRB | |
| SCHEMBL23304089 | 0.78 | PTPRB (0.58) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133232-A1 | METHODS FOR MANUFACTURE OF SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint Pharmaceuticals, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |