Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535019 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL27233066 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL27233064 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24535187 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24535002 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24534722 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24535188 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24535050 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL24534724 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9ASTS | |
| SCHEMBL27233065 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9ASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129951-A1 | PHARMACEUTICAL COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |