Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679998 | 1.00 | KRAS (0.51) | KRAS | |
| SCHEMBL24535692 | 1.00 | KRAS (0.51) | KRAS | |
| SCHEMBL30706592 | 0.90 | KRAS (0.44) | KRAS | |
| SCHEMBL24536089 | 0.90 | KRAS (0.56) | KRAS | |
| SCHEMBL30707184 | 0.90 | KRAS (0.44) | KRAS | |
| SCHEMBL24535718 | 0.90 | KRAS (0.56) | KRAS | |
| SCHEMBL24535697 | 0.90 | KRAS (0.56) | KRAS | |
| SCHEMBL29680243 | 0.90 | KRAS (0.56) | KRAS | |
| SCHEMBL30922600 | 0.90 | KRAS (0.49) | KRAS | |
| SCHEMBL24536098 | 0.90 | KRAS (0.49) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132200-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |