⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306407 | 0.70 | — | — | |
| SCHEMBL26111792 | 0.67 | MEN1 (0.47) | — | |
| SCHEMBL11989335 | 0.67 | — | — | |
| SCHEMBL26110338 | 0.67 | MEN1 (0.47) | — | |
| SCHEMBL11897586 | 0.67 | MEN1 (0.47) | — | |
| SCHEMBL26110667 | 0.67 | MEN1 (0.47) | — | |
| SCHEMBL822524 | 0.64 | — | — | |
| SCHEMBL19372809 | 0.64 | — | — | |
| SCHEMBL17901856 | 0.64 | — | — | |
| SCHEMBL5781031 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544676-A1 | THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS | The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112867-A1 | THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2011-09-15 | — | — | WO | disclosed |