Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535809 | 0.93 | KRAS (0.51) | KRAS | |
| SCHEMBL24537151 | 0.89 | KRAS (0.46) | KRAS | |
| SCHEMBL24535793 | 0.89 | KRAS (0.48) | KRAS | |
| SCHEMBL24537107 | 0.87 | KRAS (0.47) | KRAS | |
| SCHEMBL24536334 | 0.87 | KRAS (0.51) | KRAS | |
| SCHEMBL24537083 | 0.87 | KRAS (0.46) | KRAS | |
| SCHEMBL24536296 | 0.87 | KRAS (0.47) | KRAS | |
| SCHEMBL24536245 | 0.86 | KRAS (0.44) | KRAS | |
| SCHEMBL24536120 | 0.85 | KRAS (0.45) | KRAS | |
| SCHEMBL24536562 | 0.85 | KRAS (0.50) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132200-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |