SCHEMBL24539211

SCHEMBL24539211

C[C@H]1CCC[C@@H]1n1cc(C(N)=O)c(N)n1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK1 P23458 20/20 0.40
JAK2 O60674 19/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24538790 1.00 JAK1 (0.40) JAK1JAK2
SCHEMBL20039719 0.97 JAK1 (0.40) JAK1JAK2
SCHEMBL24525979 0.97 JAK1 (0.40) JAK1JAK2
SCHEMBL19192612 0.97 JAK1 (0.40) JAK1JAK2
SCHEMBL24525986 0.82 JAK2 (0.45) JAK1JAK2
SCHEMBL22103871 0.82 JAK2 (0.45) JAK1JAK2
SCHEMBL19190980 0.82 JAK1 (0.38) JAK1JAK2
SCHEMBL27860905 0.81 BTK (0.49) JAK1JAK2
SCHEMBL24526262 0.79 JAK1 (0.63) JAK1JAK2
SCHEMBL24526295 0.79 JAK1 (0.63) JAK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022133420-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2022-06-23 WO disclosed