Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24539505 | 0.84 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL24539627 | 0.77 | TLR7 (0.68) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25301768 | 0.76 | TLR7 (0.46) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539515 | 0.76 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL24539640 | 0.76 | TLR7 (0.55) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539495 | 0.75 | TLR7 (0.51) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539651 | 0.74 | TLR7 (0.50) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31270935 | 0.74 | TLR7 (0.52) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25258665 | 0.74 | TLR7 (0.52) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24539487 | 0.74 | TLR7 (0.58) | TLR7PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126263-A1 | IMIDAZOTHIENOPYRIDINE COMPOUNDS AND METHODS OF USE | ZYMEWORKS INC. (CA) | 2022-06-23 | — | — | WO | disclosed |