Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ANXA2 | P07355 | 3/20 | 0.34 |
| ▸ | S100A10 | P60903 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25576425 | 1.00 | HSD17B10 (0.39) | HSD17B10ALDH1A1SMN1; SMN2ANXA2S100A10 | |
| SCHEMBL12327042 | 1.00 | HSD17B10 (0.39) | HSD17B10ALDH1A1SMN1; SMN2ANXA2S100A10 | |
| SCHEMBL12327463 | 1.00 | HSD17B10 (0.39) | HSD17B10ALDH1A1SMN1; SMN2ANXA2S100A10 | |
| SCHEMBL25576420 | 0.91 | HSD17B10 (0.33) | HSD17B10ALDH1A1SMN1; SMN2ANXA2S100A10 | |
| SCHEMBL13381316 | 0.89 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL8036136 | 0.89 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL10563724 | 0.87 | HSD17B10 (0.45) | HSD17B10ALDH1A1SMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL5538919 | 0.87 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2SLC6A9 | |
| SCHEMBL7885790 | 0.87 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2SLC6A9 | |
| SCHEMBL3930061 | 0.87 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126275-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-23 | — | — | WO | disclosed |