Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22970047 | 0.83 | — | — | |
| SCHEMBL22969929 | 0.83 | — | — | |
| SCHEMBL24543198 | 0.83 | JAK3 (0.33) | — | |
| SCHEMBL24876304 | 0.81 | KRAS (0.35) | KRAS | |
| SCHEMBL24876392 | 0.81 | KRAS (0.35) | KRAS | |
| SCHEMBL25446258 | 0.80 | KRAS (0.39) | KRAS | |
| SCHEMBL25066432 | 0.79 | KRAS (0.34) | KRAS | |
| SCHEMBL22969799 | 0.78 | — | — | |
| SCHEMBL22969919 | 0.78 | EGFR (0.32) | — | |
| SCHEMBL24543362 | 0.78 | KRAS (0.35) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127827-A1 | KRASG12C PROTEIN MUTATION INHIBITOR AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-06-23 | — | — | WO | disclosed |