Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.86 |
| ▸ | FGFR2 | P21802 | 18/20 | 0.86 |
| ▸ | FGFR3 | P22607 | 16/20 | 0.86 |
| ▸ | FGFR4 | P22455 | 14/20 | 0.86 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547534 | 0.92 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547728 | 0.89 | FGFR1 (0.83) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547721 | 0.89 | FGFR1 (0.85) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547558 | 0.88 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547527 | 0.87 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547687 | 0.85 | FGFR1 (0.73) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547557 | 0.84 | FGFR1 (0.85) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547540 | 0.84 | FGFR1 (0.85) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547732 | 0.83 | FGFR1 (0.73) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547585 | 0.81 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127261-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | 天津济坤医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |