Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 0.88 |
| ▸ | FGFR2 | P21802 | 17/20 | 0.88 |
| ▸ | FGFR3 | P22607 | 15/20 | 0.88 |
| ▸ | FGFR4 | P22455 | 12/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547547 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547549 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547545 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547544 | 0.93 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547543 | 0.91 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL26165827 | 0.91 | FGFR1 (0.91) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547589 | 0.90 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24862026 | 0.88 | FGFR1 (0.94) | FGFR1FGFR2FGFR3FGFR4KCNH2 | |
| SCHEMBL24547567 | 0.87 | FGFR2 (1.00) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL24547538 | 0.86 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127261-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | 天津济坤医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |