Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600737 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30511861 | 0.80 | PRF1 (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL245940 | 0.80 | PRF1 (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13913511 | 0.79 | PRF1 (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15169500 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1930548 | 0.78 | ADORA1 (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3348164 | 0.78 | CA12 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31378302 | 0.78 | CA12 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL245866 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13929770 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588454-A1 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012000945-A1 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-05 | — | — | WO | disclosed |