Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.67 |
| ▸ | BRAF | P15056 | 18/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.60 |
| ▸ | KIT | P10721 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890087 | 0.86 | RAF1 (0.72) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL13211224 | 0.83 | RAF1 (0.73) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2894734 | 0.83 | BRAF (0.80) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2889608 | 0.83 | BRAF (0.59) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2886718 | 0.82 | RAF1 (0.77) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2892717 | 0.82 | RAF1 (0.77) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2895421 | 0.81 | BRAF (0.78) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2892695 | 0.81 | RAF1 (0.78) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2894441 | 0.81 | RAF1 (0.91) | RAF1BRAFKDRLCKFYN | |
| SCHEMBL2894951 | 0.81 | RAF1 (1.00) | RAF1BRAFKDRLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |