Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24549208 | 1.00 | HRH4 (0.37) | HRH4SMPD3TSHRKDM4ELMNA | |
| SCHEMBL24549027 | 1.00 | HRH4 (0.37) | HRH4SMPD3TSHRKDM4ELMNA | |
| SCHEMBL15932002 | 0.98 | HRH4 (0.38) | HRH4SMPD3KDM4ELMNAHSD17B10 | |
| SCHEMBL2706590 | 0.94 | HRH4 (0.35) | HRH4SMPD3KDM4ELMNAHSD17B10 | |
| SCHEMBL24486070 | 0.76 | MEN1 (0.33) | HRH4SMPD3TSHR | |
| SCHEMBL18238079 | 0.73 | PDCD1 (0.40) | KDM4E | |
| SCHEMBL18238080 | 0.73 | TAAR1 (0.31) | — | |
| SCHEMBL24549487 | 0.73 | — | — | |
| SCHEMBL17128162 | 0.72 | HAVCR2 (0.47) | HRH4SMPD3TSHRKDM4E | |
| SCHEMBL10281378 | 0.72 | HAVCR2 (0.47) | HRH4SMPD3TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133098-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |