⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765813 | 0.92 | — | — | |
| Butadiene SCHEMBL2764815 | 0.90 | — | — | |
| SCHEMBL9974274 | 0.84 | DYRK1A (0.39) | — | |
| SCHEMBL2455162 | 0.82 | CYP19A1 (0.39) | — | |
| Butadiene SCHEMBL2766098 | 0.74 | CYP19A1 (0.34) | — | |
| SCHEMBL256698 | 0.73 | — | — | |
| SCHEMBL2767166 | 0.73 | KDM5A (0.38) | — | |
| SCHEMBL294541 | 0.71 | — | — | |
| SCHEMBL22183930 | 0.71 | — | — | |
| SCHEMBL13547964 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371831-B1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9133098-B2 | Process for producing organolithium compound and process for producing substituted aromatic compound | NIPPON SODA CO., LTD. (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20150025276-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO., LTD. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-8871970-B2 | Process for producing organolithium compound and process for producing substituted aromatic compound | NIPPON SODA CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| EP-2371831-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | Nippon Soda Co., Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110224457-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO., LTD. | 2011-09-15 | — | — | US | disclosed |
| US-7368516-B2 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20050187419-A1 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2005-08-25 | — | — | US | disclosed |
| US-6900152-B2 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20020035029-A1 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2002-03-21 | — | — | US | disclosed |