Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24554165 | 0.90 | MAPK14 (0.43) | MAPK14MAPK10CSNK1DCSNK1EEGFR | |
| SCHEMBL24554397 | 0.87 | MAPK14 (0.44) | MAPK14MAPK10CSNK1DCSNK1E | |
| SCHEMBL24554168 | 0.87 | KCNK3 (0.38) | MAPK14MAPK10CSNK1DCSNK1E | |
| SCHEMBL24554390 | 0.86 | EGFR (0.40) | MAPK14MAPK10CSNK1DCSNK1EEGFR | |
| SCHEMBL24554229 | 0.84 | MAPK14 (0.41) | MAPK14MAPK10CSNK1DCSNK1E | |
| SCHEMBL24554150 | 0.83 | NR3C2 (0.44) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL29683274 | 0.83 | NR3C2 (0.44) | MAPK14CSNK1DCSNK1E | |
| SCHEMBL24554157 | 0.83 | MAPK14 (0.38) | MAPK14MAPK10CSNK1DEGFRRAF1 | |
| SCHEMBL24553697 | 0.82 | MAPK14 (0.53) | MAPK14MAPK10CSNK1D | |
| SCHEMBL25223642 | 0.82 | NR3C2 (0.46) | MAPK14MAPK10CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |