Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.80 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.80 |
| ▸ | LDHB | P07195 | 3/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.41 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335203 | 0.96 | KDM1A (0.79) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL17992356 | 0.96 | KDM1A (0.79) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL19982014 | 0.93 | KDM1A (0.83) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL29692248 | 0.93 | KDM1A (0.83) | KDM1ARCOR1LDHBSSTR5EGFR | |
| Desfa-[Dab1]Polymyxin B SCHEMBL29354296 | 0.92 | KDM1A (0.86) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL21335145 | 0.91 | KDM1A (0.88) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL16426328 | 0.91 | KDM1A (0.84) | KDM1ARCOR1LDHBSSTR5SSTR2 | |
| SCHEMBL16426297 | 0.91 | KDM1A (0.88) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL17655763 | 0.91 | KDM1A (0.81) | KDM1ARCOR1LDHBSSTR5EGFR | |
| SCHEMBL17655767 | 0.91 | KDM1A (0.81) | KDM1ARCOR1LDHBSSTR5EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999711-B1 | POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS | SPERO THERAPEUTICS INC (US) | 2022-06-29 | — | — | EP | disclosed |