Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24566258 | 1.00 | BRD4 (0.36) | BRD4CREBBPCNR2CNR1MAP3K12 | |
| SCHEMBL24007022 | 0.88 | CNR2 (0.35) | CNR2 | |
| SCHEMBL24007028 | 0.88 | CNR2 (0.35) | CNR2 | |
| SCHEMBL24566070 | 0.83 | MAP3K12 (0.34) | MAP3K12 | |
| SCHEMBL24565651 | 0.81 | MAP3K12 (0.32) | MAP3K12 | |
| SCHEMBL24566631 | 0.81 | MAP3K12 (0.32) | MAP3K12 | |
| SCHEMBL24007866 | 0.81 | PDE4D (0.32) | — | |
| SCHEMBL24816262 | 0.81 | BRD4 (0.39) | BRD4CREBBPCNR2CNR1MAP3K12 | |
| SCHEMBL24007247 | 0.80 | BRD4 (0.39) | BRD4CREBBPCNR2CNR1MAP3K12 | |
| SCHEMBL24007404 | 0.80 | BRD4 (0.39) | BRD4CREBBPCNR2CNR1MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267574-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022140527-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022140527-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |