Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236193 | 0.85 | KMT2A (0.53) | KMT2APOLBL3MBTL1HPGDGAA | |
| SCHEMBL8345429 | 0.85 | GAA (0.54) | KMT2APOLBL3MBTL1HPGDGAA | |
| SCHEMBL13850690 | 0.83 | KMT2A (0.56) | KMT2APOLBL3MBTL1HPGDGAA | |
| SCHEMBL799655 | 0.76 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2ALDH1A1MMP1MMP2 | |
| SCHEMBL13458546 | 0.76 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2ALDH1A1MMP1MMP2 | |
| SCHEMBL23480155 | 0.76 | SMN1; SMN2 (0.51) | KMT2APOLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7262590 | 0.76 | SMN1; SMN2 (0.51) | KMT2APOLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3987200 | 0.76 | GAA (0.46) | KMT2APOLBL3MBTL1GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.74 | GAA (0.67) | POLBL3MBTL1GAAMGAMSI | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.74 | GAA (0.67) | POLBL3MBTL1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |