Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568199 | 0.83 | KMT2A (0.46) | KMT2APOLBFPR2APOBEC3AAPOBEC3G | |
| SCHEMBL4408729 | 0.77 | KMT2A (0.51) | KMT2APOLBFPR2APOBEC3AAPOBEC3G | |
| SCHEMBL11967051 | 0.73 | KMT2A (0.54) | KMT2APOLBFPR2MEN1LMNA | |
| SCHEMBL16256882 | 0.73 | KMT2A (0.58) | KMT2APOLBFPR2MEN1LMNA | |
| SCHEMBL8165986 | 0.73 | KMT2A (0.68) | KMT2APOLBMEN1LMNATSHR | |
| SCHEMBL8161187 | 0.72 | APOBEC3A (0.43) | KMT2APOLBFPR2APOBEC3AAPOBEC3G | |
| SCHEMBL13753309 | 0.72 | POLB (0.65) | KMT2APOLBMEN1LMNATSHR | |
| SCHEMBL14493755 | 0.70 | POLB (0.43) | KMT2APOLBMEN1LMNAALDH1A1 | |
| SCHEMBL11677768 | 0.70 | POLB (0.74) | KMT2APOLBMEN1LMNATSHR | |
| SCHEMBL11955141 | 0.69 | POLB (0.56) | KMT2APOLBFPR2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |