Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823698 | 0.86 | MEN1 (0.83) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL22924507 | 0.85 | MEN1 (0.47) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL15204485 | 0.83 | MEN1 (0.73) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL24567583 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24571814 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL21467394 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL799662 | 0.81 | KMT2A (0.75) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL31445767 | 0.81 | POLB (0.47) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL23689650 | 0.80 | MEN1 (0.73) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL18896250 | 0.79 | MEN1 (0.71) | MEN1KMT2AALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |