Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547562 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2PKMHTTCTSSNPC1 | |
| SCHEMBL8392709 | 0.84 | SMN1; SMN2 (0.96) | SMN1; SMN2PKMHTTCTSSNPC1 | |
| SCHEMBL22436193 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTNPC1RAB9A | |
| SCHEMBL24567519 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTNPC1RAB9A | |
| SCHEMBL14752974 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTKMT2ACYP2C9 | |
| SCHEMBL24567507 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTKMT2ACYP2C9 | |
| SCHEMBL21142539 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2PKMHTTCTSSNPC1 | |
| SCHEMBL16580220 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2PKMHTTCTSSNPC1 | |
| SCHEMBL15876247 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2PKMHTTCTSSNPC1 | |
| SCHEMBL15429761 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2PKMHTTCTSSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |