Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24570031 | 0.80 | — | — | |
| SCHEMBL19757257 | 0.71 | — | — | |
| SCHEMBL12374718 | 0.71 | — | — | |
| SCHEMBL24570027 | 0.70 | PIM1 (0.32) | — | |
| SCHEMBL12374763 | 0.63 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL1339261 | 0.61 | — | — | |
| SCHEMBL15254945 | 0.59 | — | — | |
| SCHEMBL717518 | 0.59 | BRD4 (0.43) | MEN1KMT2A | |
| SCHEMBL18745661 | 0.58 | — | — | |
| SCHEMBL232823 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140769-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |