Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995893 | 0.80 | PPM1B (0.52) | PPM1BPTPN1PPP1CCCYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL29025230 | 0.73 | GABRR1 (0.42) | CYP1A2GABRR1GABRR2 | |
| SCHEMBL28287653 | 0.72 | PPM1B (0.60) | PPM1BPTPN1PPP1CCCYP2C19 | |
| SCHEMBL21688328 | 0.72 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCYP2C19ALDH1A1 | |
| SCHEMBL13658097 | 0.71 | PPM1B (0.44) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL3148808 | 0.70 | — | — | |
| SCHEMBL31170695 | 0.68 | — | — | |
| SCHEMBL25602783 | 0.68 | — | — | |
| SCHEMBL31170037 | 0.68 | — | — | |
| SCHEMBL31170709 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140555-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |