SCHEMBL245726

SCHEMBL245726

CCCCCc1cn(CCCCC)c(CCCCC)n1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 12/20 0.49
KCNH2 Q12809 1/20 0.43
MIF P14174 1/20 0.42
SPNS2 Q8IVW8 2/20 0.39
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28403001 0.91 TLR8 (0.43) TLR8KCNH2MIFSPNS2GABRA2
SCHEMBL5285380 0.87 TLR8 (0.62) TLR8KCNH2SPNS2
SCHEMBL5815814 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5294354 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5291171 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5293716 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5812569 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5297208 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5307712 0.86 TLR8 (0.61) TLR8KCNH2SPNS2
SCHEMBL5305611 0.86 TLR8 (0.61) TLR8KCNH2SPNS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3119 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005683-A Hindered amine damping agent, preparation method and application thereof, underwater sound absorption rubber composite material and preparation method thereof 株洲时代新材料科技股份有限公司 2024-05-10 CN claimed
CN-117886848-A Imidazole ionic liquid for mixing trans-butyl-pentyl rubber as well as preparation method and application thereof 株洲时代新材料科技股份有限公司 2024-04-16 CN claimed
CN-112062721-B HABI photoinitiator capable of improving system stability and application thereof 常州正洁智造科技有限公司 2023-06-30 CN claimed
CN-115729035-A Transfer film for vapor deposition mask formation and method for manufacturing vapor deposition mask 富士胶片株式会社 2023-03-03 CN claimed
CN-111752096-B Photosensitive resin composition for color filter and color filter 常州正洁智造科技有限公司 2022-10-14 CN claimed
CN-111752091-B Application of HABI mixed photoinitiator in UVLED photocuring 常州正洁智造科技有限公司 2022-09-06 CN claimed
US-20210161772-A1 RADICAL POLYMERISATION INITIATORS FOR LIGHT-CURABLE DENTAL MATERIALS DENTSPLY SIRONA INC. (US) 2021-06-03 US claimed
CN-112485967-A Photoresist composition for TFT-LCD 安徽邦铭新材料科技有限公司 2021-03-12 CN claimed
CN-112062721-A HABI photoinitiator capable of improving system stability and application thereof 常州正洁智造科技有限公司 2020-12-11 CN claimed
WO-2020233700-A1 HABI PHOTOINITIATOR CAPABLE OF IMPROVING SYSTEM STABILITY AND APPLICATION THEREOF 常州格林感光新材料有限公司 (CN) 2020-11-26 WO claimed
US-4812399-A ENZYMES, HYDROLASES OR OXIDASES, LEUCO DYES EASTMAN KODAK COMPANY (US) 1989-03-14 US claimed
EP-0304163-A2 Analytical element having stabilized peroxidase EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-02-22 EP claimed
US-4788140-A OPTICAL DENSITY, FILTER DYE EASTMAN KODAK COMPANY (US) 1988-11-29 US claimed
EP-0291321-A2 Element and method for determination of creatinine or creatine EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-11-17 EP claimed
EP-0252750-A1 Composition and analytical element having stabilized peroxidase EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-01-13 EP claimed
EP-0243066-A2 Element and method for the determination of creatinine or creatine EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-10-28 EP claimed
US-RE32016-E A LACTASE OXIDASE, A SUBSTANCE HAVING PEROXIDATIVE ACTIVE, AND A MATERIAL THAT UNDERGOES DETECTABLE CHANGE EASTMAN KODAK COMPANY (US) 1985-10-29 US claimed
US-4184923-A OXIDIZING ENZYME; PEROXIDASE; INDICATOR AND SOLVENT FOR SAME EASTMAN KODAK COMPANY (US) 1980-01-22 US claimed
US-4166763-A BY MEASURING AMOUNT OF HYDROGEN PEROXIDE PRODUCED EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4089747-A OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE EASTMAN KODAK COMPANY (US) 1978-05-16 US claimed