Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 9/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.39 |
| ▸ | EIF2AK4 | Q9P2K8 | 4/20 | 0.39 |
| ▸ | NRAS | P01111 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574187 | 1.00 | FLT3 (0.45) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24574147 | 0.92 | FLT3 (0.42) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL26358740 | 0.90 | FLT3 (0.49) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL26358853 | 0.90 | FLT3 (0.49) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24573972 | 0.90 | FLT3 (0.49) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24574510 | 0.89 | FLT3 (0.46) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24574583 | 0.89 | FLT3 (0.44) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24574432 | 0.89 | USP30 (0.39) | FLT3USP30EIF2AK4CCNT1 | |
| SCHEMBL24231443 | 0.88 | FLT3 (0.48) | FLT3USP30IRAK4EIF2AK4NRAS | |
| SCHEMBL24574165 | 0.87 | FLT3 (0.42) | FLT3USP30IRAK4EIF2AK4NRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140647-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2022-06-30 | — | — | WO | disclosed |