Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Felbamate SCHEMBL2946508 | 0.87 | CYP1A2 (1.00) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL34947 | 0.87 | CYP1A2 (1.00) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL7153063 | 0.85 | CYP1A2 (0.96) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| Felbamate SCHEMBL17597519 | 0.85 | CYP1A2 (0.96) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL7775519 | 0.85 | CYP1A2 (0.71) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL27446892 | 0.84 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL23303256 | 0.84 | CYP1A2 (0.51) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL8392182 | 0.83 | CYP1A2 (0.83) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL8392180 | 0.83 | CYP1A2 (0.83) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL8056124 | 0.83 | CYP1A2 (0.83) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140705-A1 | PRODRUGS OF PHARMACEUTICAL AGENTS | ALMARSSON ORN (US) | 2022-06-30 | — | — | WO | disclosed |