SCHEMBL2457458

SCHEMBL2457458

CCCCOc1ccc(/C=C(/C)C(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
PDE4D Q08499 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.48
TP53 P04637 1/20 0.47
PLA2G4A P47712 1/20 0.47
PLA2G4B P0C869 2/20 0.46
SAE1 Q9UBE0 1/20 0.46
UBA2 Q9UBT2 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 2/20 0.44
RARB P10826 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457460 1.00 TSHR (0.50) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2483695 0.97 TSHR (0.51) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2483692 0.97 TSHR (0.51) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2483740 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2451425 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2451657 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2451422 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2451286 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2483737 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9
SCHEMBL2451658 0.96 TP53 (0.53) TSHRLMNACYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-0747461-B1 Polymer stabilized liquid crystals and flexible devices thereof SNIARICERCHE S C P A (IT) 2001-09-05 EP disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 US disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0803525-A2 Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals Sniaricerche S.C.P.A. (IT) 1997-10-29 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed