⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267734 | 0.90 | — | — | |
| SCHEMBL24267736 | 0.84 | — | — | |
| SCHEMBL24618878 | 0.75 | — | — | |
| SCHEMBL16448446 | 0.73 | GRIN2D (0.30) | — | |
| SCHEMBL20416015 | 0.68 | — | — | |
| SCHEMBL8495948 | 0.65 | — | — | |
| SCHEMBL2292661 | 0.64 | — | — | |
| SCHEMBL24267732 | 0.63 | — | — | |
| SCHEMBL6889514 | 0.61 | GRIN2D (0.31) | — | |
| SCHEMBL17487285 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269399-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022135572-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |