Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 18/20 | 0.46 |
| ▸ | CCNK | O75909 | 18/20 | 0.46 |
| ▸ | CDK9 | P50750 | 18/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.46 |
| ▸ | CDK2 | P24941 | 15/20 | 0.46 |
| ▸ | CDK7 | P50613 | 5/20 | 0.42 |
| ▸ | CCNH | P51946 | 5/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588160 | 0.87 | CLK1 (0.51) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL30221492 | 0.85 | CCNT1 (0.57) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL17696390 | 0.85 | CCNT1 (0.57) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL30456841 | 0.85 | CCNT1 (0.59) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588198 | 0.85 | CCNT1 (0.51) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24900464 | 0.84 | CCNT1 (0.48) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL30957488 | 0.84 | CCNT1 (0.48) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29492561 | 0.83 | CCNT1 (0.46) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588987 | 0.83 | RPS6KA5 (0.43) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29492558 | 0.83 | CCNT1 (0.57) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269403-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | GT Apeiron Therapeutics Limited (HK) | 2023-11-01 | — | — | EP | disclosed |
| EP-4269402-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | GT Apeiron Therapeutics Limited (HK) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |
| WO-2022134641-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |