Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102473 | 0.84 | EPHX2 (0.64) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15152979 | 0.82 | EPHX2 (0.51) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30638608 | 0.82 | EPHX2 (0.51) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23817183 | 0.82 | EPHX2 (0.51) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29856034 | 0.80 | EPHX2 (0.50) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13195798 | 0.80 | EPHX2 (0.50) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19688352 | 0.80 | EPHX2 (0.58) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5590880 | 0.80 | EPHX2 (0.58) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5590888 | 0.80 | EPHX2 (0.58) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5590882 | 0.80 | EPHX2 (0.58) | EPHX2EPHX1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135442-A1 | CDK2 INHIBITOR AND PREPARATION METHOD THEREFOR | 上海拓界生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |