Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | PTPRF | P10586 | 2/20 | 0.46 |
| ▸ | PTPRA | P18433 | 2/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254388 | 0.82 | PTPN1 (0.52) | PTPN1PTPRFPTPRAACLYIKBKB | |
| SCHEMBL2250633 | 0.82 | PTPN1 (0.52) | PTPN1PTPRFPTPRAACLYIKBKB | |
| SCHEMBL2158011 | 0.82 | PTPN1 (0.47) | PTPN1PTPRFPTPRAACLYIKBKB | |
| SCHEMBL2247145 | 0.81 | PTPN1 (0.49) | PTPN1PTPRFPTPRAACLYIKBKB | |
| SCHEMBL2252377 | 0.80 | PTPN1 (0.55) | PTPN1PTPRFPTPRAACLYMEN1 | |
| SCHEMBL2251240 | 0.80 | PTPN1 (0.47) | PTPN1PTPRFPTPRAACLYIKBKB | |
| SCHEMBL2158083 | 0.78 | PTPN1 (0.58) | PTPN1PTPRFPTPRAIKBKBMEN1 | |
| SCHEMBL2250470 | 0.78 | PTPN1 (0.52) | PTPN1PTPRFPTPRAIKBKBMEN1 | |
| SCHEMBL3811151 | 0.76 | PTPN1 (0.50) | PTPN1PTPRFPTPRAIKBKBMEN1 | |
| SCHEMBL2251143 | 0.76 | PTPN1 (0.50) | PTPN1PTPRFPTPRAIKBKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363396-A1 | Thiophene derivatives as antiviral agents for flavivirus infection | Virochem Pharma Inc. (CA) | 2011-09-07 | — | — | EP | disclosed |