Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.63 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.63 |
| ▸ | CDK2 | P24941 | 14/20 | 0.63 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.63 |
| ▸ | CDK9 | P50750 | 12/20 | 0.63 |
| ▸ | CDK7 | P50613 | 9/20 | 0.50 |
| ▸ | CCNH | P51946 | 9/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204068 | 1.00 | CCNK (0.63) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL25597463 | 1.00 | CCNK (0.63) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL30203953 | 0.90 | CDK2 (0.49) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL21179237 | 0.89 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL21188444 | 0.88 | CCNK (0.54) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24583204 | 0.88 | CCNK (0.52) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL29749443 | 0.87 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL24583163 | 0.87 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL21188533 | 0.87 | CDK2 (0.53) | CCNKCDK12CDK2CCNE1CCNT1 | |
| SCHEMBL29083554 | 0.87 | CDK2 (0.53) | CCNKCDK12CDK2CCNE1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269403-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | GT Apeiron Therapeutics Limited (HK) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |