SCHEMBL2459290

SCHEMBL2459290

C=CC(=O)OCCC(=O)OCCOC(=O)CCOC(=O)C=C

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.64
ALDH1A1 P00352 4/20 0.64
TP53 P04637 3/20 0.64
HIF1A Q16665 3/20 0.64
HSD17B10 Q99714 1/20 0.64
CYP3A4 P08684 2/20 0.58
HPGD P15428 1/20 0.52
THRB P10828 3/20 0.52
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DGKA P23743 1/20 0.39
ADRA2A P08913 1/20 0.37
ADRA1A P35348 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
ATM Q13315 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143157 1.00 TSHR (0.64) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9280497 0.94 TSHR (0.76) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9141648 0.94 TSHR (0.76) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL242130 0.94 TSHR (0.76) TSHRALDH1A1TP53HIF1AHSD17B10
Propene SCHEMBL4273406 0.94 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL17119709 0.93 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL303596 0.93 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL25967152 0.92 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL2467554 0.91 TSHR (0.72) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL25323212 0.90 TSHR (0.53) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389722-A Copolymerizing unsaturated monomers with acrylated ester compound; used as absorbent NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-14 US claimed
EP-0574202-A1 Hydrophilic resin and method for production thereof NIPPON SHOKUBAI CO., LTD. (JP) 1993-12-15 EP claimed
EP-3437730-B1 METHOD FOR MANUFACTURING WATER ABSORBING AGENT NIPPON CATALYTIC CHEM IND (JP) 2024-04-17 EP disclosed
US-11719606-B2 Method and reagent for clearing biological tissue UNIVERSITY PUBLIC CORPORATION OSAKA (JP) 2023-08-08 US disclosed
US-11224857-B2 Method for manufacturing water absorbing agent NIPPON SHOKUBAI CO., LTD. (JP) 2022-01-18 US disclosed
US-20200217761-A1 METHOD AND REAGENT FOR CLEARING BIOLOGICAL TISSUE UNIVERSITY PUBLIC CORPORATION OSAKA (JP) 2020-07-09 US disclosed
EP-2116571-B1 GRANULAR WATER ABSORBER AND METHOD OF PRODUCING THE SAME NIPPON CATALYTIC CHEM IND (JP) 2019-05-01 EP disclosed
US-20190105633-A1 METHOD FOR MANUFACTURING WATER ABSORBING AGENT NIPPON SHOKUBAI CO., LTD. (JP) 2019-04-11 US disclosed
EP-3437730-A1 METHOD FOR MANUFACTURING WATER ABSORBING AGENT Nippon Shokubai Co., Ltd. (JP) 2019-02-06 EP disclosed
US-9796820-B2 Method for producing water absorbent resin NIPPON SHOKUBAI CO., LTD. (JP) 2017-10-24 US disclosed
US-9187579-B2 Particle-shaped water absorbing agent and method for producing the same NIPPON SHOKUBAI CO., LTD. (JP) 2015-11-17 US disclosed
US-20050131143-A1 Oil absorbing composition and process ROHM AND HAAS FRANCE, S.A.S. (FR) 2005-06-16 US disclosed
EP-1514658-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-16 EP disclosed
EP-1510318-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-02 EP disclosed
US-20050043458-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY 2005-02-24 US disclosed
US-20050043453-A1 Process for manufacturing polymers CHANG CHING-JEN (US) 2005-02-24 US disclosed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed
US-5389722-A Copolymerizing unsaturated monomers with acrylated ester compound; used as absorbent NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-14 US disclosed
EP-0574202-A1 Hydrophilic resin and method for production thereof NIPPON SHOKUBAI CO., LTD. (JP) 1993-12-15 EP disclosed