Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462656 | 0.94 | IGF1R (0.77) | IGF1RTNK2 | |
| SCHEMBL2460245 | 0.93 | IGF1R (0.80) | IGF1RTNK2 | |
| SCHEMBL2463479 | 0.90 | IGF1R (0.78) | IGF1R | |
| SCHEMBL2457371 | 0.89 | IGF1R (0.90) | IGF1RTNK2 | |
| SCHEMBL2457376 | 0.89 | IGF1R (0.90) | IGF1RTNK2 | |
| SCHEMBL2459993 | 0.87 | IGF1R (0.79) | IGF1RTNK2 | |
| SCHEMBL2460555 | 0.87 | IGF1R (1.00) | IGF1RTNK2 | |
| SCHEMBL2460549 | 0.87 | IGF1R (1.00) | IGF1RTNK2 | |
| SCHEMBL2463555 | 0.87 | IGF1R (1.00) | IGF1RTNK2 | |
| SCHEMBL2458135 | 0.86 | IGF1R (0.84) | IGF1RTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675860-B1 | IMIDAZO[1,5-A]PYRAZINES AS TYROSINE KINASE INHIBITORS | OSI PHARM INC (US) | 2011-09-21 | — | — | EP | claimed |
| EP-1675860-B1 | IMIDAZO[1,5-A]PYRAZINES AS TYROSINE KINASE INHIBITORS | OSI PHARM INC (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7459554-B2 | Imidazopyrazine tyrosine kinase inhibitors | OSI PHARMACEUTICALS, INC. (US) | 2008-12-02 | — | — | US | disclosed |