⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348498 | 0.92 | — | — | |
| SCHEMBL12148566 | 0.86 | — | — | |
| SCHEMBL17348501 | 0.77 | — | — | |
| SCHEMBL9912000 | 0.70 | — | — | |
| SCHEMBL12341068 | 0.69 | — | — | |
| SCHEMBL17348496 | 0.67 | — | — | |
| SCHEMBL573675 | 0.65 | — | — | |
| SCHEMBL15021957 | 0.65 | — | — | |
| SCHEMBL4638070 | 0.65 | — | — | |
| SCHEMBL4638074 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273146-A1 | TRICYCLIC COMPOUND AND USE THEREOF | Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |