Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29089586 | 0.99 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL24598893 | 0.96 | NR1H4 (0.54) | NR1H4 | |
| SCHEMBL1097117 | 0.88 | NR1H4 (0.56) | NR1H4 | |
| Hydrochloric Acid SCHEMBL1096131 | 0.87 | NR1H4 (0.55) | NR1H4 | |
| SCHEMBL1095590 | 0.83 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL24599123 | 0.82 | NR1H4 (0.48) | NR1H4 | |
| Hydrochloric Acid SCHEMBL1096206 | 0.82 | NR1H4 (0.58) | NR1H4 | |
| SCHEMBL9957598 | 0.81 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL27206904 | 0.81 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL27192352 | 0.81 | NR1H4 (0.50) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116887827-A | Compounds and methods for modulating FXR | 拓臻制药公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022147448-A1 | COMPOUNDS AND METHODS FOR MODULATING FXR | TERNS PHARMACEUTICALS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |