Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP36 | Q9P275 | 16/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600063 | 0.90 | USP36 (1.00) | USP36 | |
| SCHEMBL29749420 | 0.90 | USP36 (1.00) | USP36 | |
| SCHEMBL24600192 | 0.81 | USP36 (1.00) | USP36 | |
| SCHEMBL29499197 | 0.80 | USP36 (0.66) | USP36MAPTKCNK3LMNA | |
| SCHEMBL22617035 | 0.80 | USP36 (0.66) | USP36MAPTKCNK3LMNA | |
| SCHEMBL29749060 | 0.80 | USP36 (1.00) | USP36 | |
| SCHEMBL29531244 | 0.79 | USP36 (0.65) | USP36MAPTLMNA | |
| SCHEMBL29749057 | 0.77 | USP36 (1.00) | USP36MAPTKCNK3 | |
| SCHEMBL30926796 | 0.77 | GAA (0.66) | MAPTKCNK3LMNA | |
| SCHEMBL27179437 | 0.77 | GAA (0.66) | MAPTKCNK3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213088-A1 | INHIBITING USP36 | Valo Health, LLC | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213088-A1 | INHIBITING USP36 | USP36, USP30, USP39 | USP36 1/4885MAPT 2907/4885KCNK3 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.