Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 12/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.51 |
| ▸ | AKT2 | P31751 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26679976 | 0.99 | ENPP1 (0.52) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| Hydrochloric Acid SCHEMBL29692010 | 0.99 | ENPP1 (0.52) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL24600523 | 0.90 | ENPP1 (0.51) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| Hydrochloric Acid SCHEMBL29691554 | 0.89 | ENPP1 (0.50) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| Hydrochloric Acid SCHEMBL26679916 | 0.89 | ENPP1 (0.50) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL29691653 | 0.85 | ENPP1 (0.48) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL24600681 | 0.85 | ENPP1 (0.48) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL26679832 | 0.84 | ENPP1 (0.47) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL29248783 | 0.84 | ENPP1 (0.49) | ENPP1ROCK2ROCK1CDC42BPBAKT2 | |
| SCHEMBL24601047 | 0.84 | AKT2 (0.65) | ENPP1ROCK2ROCK1CDC42BPBAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |