Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612352 | 0.81 | BACE1 (0.41) | CYP2A6ASIC3LOXL2AGXTBACE1 | |
| SCHEMBL9374785 | 0.78 | CYP2A6 (0.60) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL13495923 | 0.77 | BACE1 (0.57) | CA2BACE1ALDH1A1KDM4EMEN1 | |
| SCHEMBL793711 | 0.77 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL11485426 | 0.77 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL31095741 | 0.77 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL3051489 | 0.77 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL122572 | 0.77 | CYP2A6 (0.58) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL31106526 | 0.77 | CYP2A6 (0.53) | CYP2A6ASIC3LOXL2CA2PTPN2 | |
| SCHEMBL6253354 | 0.77 | CYP2A6 (0.55) | CYP2A6ASIC3LOXL2CA2AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | HNRNPF, RBM3, RBM15 | CYP2A6 4654/4885ASIC3 3892/4885LOXL2 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.